A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors.

A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors.

The discovery of the enhanced permeability and retention (EPR) effect has resulted in the development of nanomedicines, including liposome-based formulations of drugs, as cancer therapies. The use of liposomes has resulted in substantial increases in accumulation of drugs in solid tumors; yet, signi...

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Bibliographic Details
Main Authors: Shawn Stapleton, Michael Milosevic, Christine Allen, Jinzi Zheng, Michael Dunne, Ivan Yeung, David A Jaffray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312530/?tool=EBI

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