A Mechanistic Model for Naive CD4 T Cell Homeostasis in Healthy Adults and Children

The size and composition of the T lymphocyte compartment is subject to strict homeostatic regulation and is remarkably stable throughout life in spite of variable dynamics in cell production and death during T cell development and immune responses. Homeostasis is achieved by careful orchestration of...

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Bibliographic Details
Main Authors: Tharindi eHapuarachchi, Joanna eLewis, Robin eCallard
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00366/full