TGFβ Is Specifically Upregulated on Circulating CD14++ CD16+ and CD14+ CD16++ Monocytes in Patients with Atrial Fibrillation and Severe Atrial Fibrosis

TGFβ Is Specifically Upregulated on Circulating CD14++ CD16+ and CD14+ CD16++ Monocytes in Patients with Atrial Fibrillation and Severe Atrial Fibrosis

Background/Aims: Fibrotic remodeling of the atria plays a key role in the pathogenesis of atrial fibrillation (AF). As little is known about the contribution of circulating monocytes in atrial remodeling and the pathophysiology of AF, we investigated profibrotic factors in different subsets of circu...

Full description

Bibliographic Details
Main Authors:	David Heinzmann, Stefan Fuß, Saskia v. Ungern-Sternberg, Jürgen Schreieck, Meinrad Gawaz, Michael Gramlich, Peter Seizer
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Atrial Fibrosis Atrial fibrillation ablation Monocyte subsets EMMPRIN Matrix metalloproteinases
Online Access:	https://www.karger.com/Article/FullText/492873

Similar Items

CD14+CD16− monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK
by: Jimeng Xue, et al.
Published: (2020-09-01)

A Novel, Five-Marker Alternative to CD16–CD14 Gating to Identify the Three Human Monocyte Subsets
by: Siew-Min Ong, et al.
Published: (2019-07-01)

Changes in the Monocytic Subsets CD14dimCD16+ and CD14++CD16− in Chronic Systolic Heart Failure Patients
by: Offer Amir, et al.
Published: (2012-01-01)

Serum CD40 ligand levels and persistent lone atrial fibrillation
by: Timuçin Altın
Published: (2016-07-01)

Upregulation of CD40/CD40L system in rheumatic mitral stenosis with or without atrial fibrillation
by: Hanan Azzam, et al.
Published: (2014-03-01)

Integrative Analyses of Genes Associated With Osteoporosis in CD16+ Monocyte
by: Bin Hu, et al.
Published: (2021-01-01)

The Biological Function and Clinical Utilization of CD147 in Human Diseases: A Review of the Current Scientific Literature
by: Lijuan Xiong, et al.
Published: (2014-09-01)

Characterization of the CD14++CD16+ monocyte population in human bone marrow.
by: Manuela Mandl, et al.
Published: (2014-01-01)

CD14CD16 Monocyte Subset Levels in Heart Failure Patients
by: Chiara Barisione, et al.
Published: (2010-01-01)

Relationship between serum level of CD40 ligand and persistent lone atrial fibrillation
by: Evin Bozçalı, et al.
Published: (2016-07-01)

Activated Platelets Convert CD14+CD16- Into CD14+CD16+ Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization
by: Su Jeong Lee, et al.
Published: (2021-01-01)

Infiltrating CD16+ Are Associated with a Reduction in Peripheral CD14+CD16++ Monocytes and Severe Forms of Lupus Nephritis
by: Anabel Barrera García, et al.
Published: (2016-01-01)

REMODELING OF THE TRANSFORMED PHENOTYPE OF CD16+CD32+CD11b+ NEUTROPHILIC GRANULOCYTES OF PATIENTS WITH ATYPICAL CHRONIC BACTERIAL INFECTION IN VITRO
by: G A Chudilova, et al.
Published: (2018-12-01)

MMP9 Rs3918242 Polymorphism Affects Tachycardia-Induced MMP9 Expression in Cultured Atrial-Derived Myocytes but Is Not a Risk Factor for Atrial Fibrillation among the Taiwanese
by: Fu-Chih Hsiao, et al.
Published: (2016-04-01)

Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16− Monocytes
by: Man K. S. Lee, et al.
Published: (2019-09-01)

DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
by: V. G. Matveeva, et al.
Published: (2014-07-01)

Fatores preditores de fibrilação atrial após ablação do flutter atrial típico Factores predictores de fibrilación atrial tras ablación del flutter atrial típico Predictors of atrial fibrillation after ablation of typical atrial flutter
by: Sissy Lara de Melo, et al.
Published: (2009-11-01)

Rapid Atrial Pacing Promotes Atrial Fibrillation Substrate in Unanesthetized Instrumented Rats
by: Wesam Mulla, et al.
Published: (2019-09-01)

Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation
by: A. V. Goryachiy, et al.
Published: (2017-05-01)

Efeitos da associação da estimulação atrial dinâmica em duplo sítio atrial com atenolol na prevenção da fibrilação atrial recorrente Effects of the association of dual-site dynamic atrial overdrive and atenolol in preventing recurrent atrial fibrillation
by: Antonio da Silva Menezes Júnior, et al.
Published: (2007-01-01)

EMMPRIN expression is associated with metastatic progression in osteosarcoma
by: Han-Soo Kim, et al.
Published: (2021-09-01)

Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice
by: Ya Suo, et al.
Published: (2019-10-01)

CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts
by: M. Aoki, et al.
Published: (2019-09-01)

Right atrial appendage thrombus with atrial infarct in a case of thyrotoxicosis: An autopsy report
by: Lanjewar D, et al.
Published: (2010-07-01)

Focal atrial fibrillation presenting in the origin of atrial tachycardia
by: Chin-Yu Lin, MD, et al.
Published: (2015-01-01)

Predictors of the atrial fibrillation following catheter ablation of typical atrial flutter
by: Majid Haghjoo, et al.
Published: (2013-01-01)

Dromedary camel CD14high MHCIIhigh monocytes display inflammatory properties and are reduced in newborn camel calves
by: Jamal Hussen, et al.
Published: (2020-02-01)

Left Atrial Hypertension, Electrical Conduction Slowing, and Mechanical Dysfunction – The Pathophysiological Triad in Atrial Fibrillation-Associated Atrial Cardiomyopathy
by: Martin Eichenlaub, et al.
Published: (2021-08-01)

Oral direct renin inhibitor aliskiren reduces in vivo oxidative stress and serum matrix metalloproteinase-2 levels in patients with permanent atrial fibrillation
by: Yoshizumi Takei, MD, et al.
Published: (2015-04-01)

Predictive value of left atrial appendage lobes on left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation
by: Fan Wang, et al.
Published: (2018-07-01)

Right atrial mass following transcatheter radiofrequency ablation for recurrent atrial fibrillation: thrombus, endocarditis or mixoma?
by: Roberta Ancona, et al.
Published: (2016-01-01)

Arrhythmogenic isolated left atrial cardiomyopathy
by: Madhu Shukla, et al.
Published: (2019-01-01)

Atrial flutter with atypical presentation
by: Vikas Kataria, et al.
Published: (2016-03-01)

Increases in inflammatory and CD14dim/CD16pos/CD45pos patrolling monocytes in sepsis: correlation with final outcome
by: Gabriela Gainaru, et al.
Published: (2018-03-01)

CD14 and CD16 expression in noninfectious granulomatous skin diseases
by: Yuta Ito, et al.
Published: (2020-02-01)

Dopamine increases CD14+CD16+ monocyte migration and adhesion in the context of substance abuse and HIV neuropathogenesis.
by: Jacqueline S Coley, et al.
Published: (2015-01-01)

Proinflammatory CD14+CD16+ monocytes are associated with vascular stiffness in predialysis patients with chronic kidney disease
by: Jae-Won Lee, et al.
Published: (2013-12-01)

Proinflammatory (CD14+CD16++) monocytes in type 2 diabetes mellitus patients with/without chronic periodontitis
by: Raghunathan Jagannathan, et al.
Published: (2019-01-01)

The Expression of CD14+CD16+ Monocyte Subpopulation in Coronary Heart Disease Patients with Blood Stasis Syndrome
by: Ye Huang, et al.
Published: (2013-01-01)

Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
by: Hakan Gunes, et al.
Published: (2018-08-01)