Short-Term Diet Restriction but Not Alternate Day Fasting Prevents Cisplatin-Induced Nephrotoxicity in Mice

Short-Term Diet Restriction but Not Alternate Day Fasting Prevents Cisplatin-Induced Nephrotoxicity in Mice

Cisplatin (CP) is one of the most preferred platinum-containing antineoplastic drugs. However, even in nontoxic plasma concentrations, it may cause kidney injury. To be able to increase its effective pharmacological dose, its side effects need to be regarded. Diet restriction (DR) has been demonstra...

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Bibliographic Details
Main Authors: Evrin Gunebakan, Esra Yalcin, Esra Cikler Dulger, Ahmet Yigitbasi, Nilay Ates, Aysun Caglayan, Mustafa C. Beker, Kazim Sahin, Hasan Korkaya, Ertugrul Kilic
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomedicines
Subjects:
cisplatin
fasting
renal protection
acute kidney injury
nephrotoxicity
mapk pathway
Online Access:https://www.mdpi.com/2227-9059/8/2/23

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