Immunohistochemical investigation of neuroendocrine component in prostate adenocarcinoma

• Main Authors: Prokopyk O. V., Kuryk O. G., Andreyev M. D.
• Format: Article
• Language: Russian
• Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2010-01-01
• Series: Морфологія
• Subjects: prostate adenocarcinoma; neuroendocrine differentiation; immunohistochemical investigation; chromogranin A; neuron-specific enolase
• Online Access: http://www.morphology.dp.ua/_pub/MORPHO-2010-04-03/10povapz.pdf
• ISSN: 1997-9665

A purpose of current research was to investigate the neuroendocrine component of prostate adenocarcinoma. The immunohistochemical investigation with using markers of neuroendocine differentiation – chromogranin A and neuronspecific enolase was performed. The neuroendocrine differentiation in light-cell adenocarcinoma is more expressive comparing with poorly dark-cell adenocarcinoma, and the neuroendocrine differentiation in moderately differentiated adenocarcinoma is more expressive comparing with poorly differentiated adenocarcinoma.