Rare Paravertebral and Skull Base Metastases in Prostate Cancer

• Main Authors: Gbeminiyi Samuel, Amir Isbell, Onyekachi Ogbonna, Hasan Iftikhar, Susmita Sakruti, Adebayo Atanda, Raj P. Manchandani
• Format: Article
• Language: English
• Published: Karger Publishers 2016-11-01
• Series: Case Reports in Oncology
• Subjects: Paravertebral metastasis; Skull base metastasis; Mixed sclerotic and lytic lesions; Prostate cancer
• Online Access: http://www.karger.com/Article/FullText/452327

Prostate cancer is the most commonly diagnosed visceral cancer in the United States. A majority of cases exhibit an insidious course and nonaggressive tumor behavior. Prostate cancer can manifest as lesions which remain localized, regionally invading or metastasize to lymph nodes, bones, and lungs. Here, we report a unique case of metastatic prostate cancer to the right upper mediastinum, presenting as a paravertebral mass within 2 years of initial tissue diagnosis. Paravertebral spread has not been described for prostate cancer, and herein, we discuss the clinical presentation, diagnostic workup, and possible therapeutic options available in light of the literature.