Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer

<p>Abstract</p> <p>Background</p> <p>Thymidylate synthase (TS) is a critical target for cancer chemotherapy and is one of the most extensively studied biomarkers for fluoropyrimidine-based chemotherapy. In addition to its critical role in enzyme catalysis, TS functions...

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Bibliographic Details
Main Authors: Chu Edward, Schmitz John C, Nakajima Go, Xi Yaguang, Ju Jingfang
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/7/68