FEASIBILITY OF DIRECT SOLID SAMPLING FOR ARSENIC DETERMINATION IN SULFUR-CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS BY GF AAS

FEASIBILITY OF DIRECT SOLID SAMPLING FOR ARSENIC DETERMINATION IN SULFUR-CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS BY GF AAS

A method for As determination in sulfur-containing active pharmaceutical ingredients (SC-APIs) by direct solid sampling graphite furnace atomic absorption (DSS-GF AAS) was developed. The proposed method was successfully applied to three SC-APIs (hydrochlorothiazide, furosemide and sulfadiazine). Pal...

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Bibliographic Details
Main Authors: Erico Marlon Moraes Flores, Fabio Andrei Duarte, Gabriel Toneto Druzian, Mariele Samuel Nascimento, Juliano Smanioto Barin, Rodrigo Cordeiro Bolzan
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2019-07-01
Series:Drug Analytical Research
Subjects:
arsenic determination
solid sampling
graphite furnace atomic absorption spectrometry
elemental impurities determination
toxic elements
Online Access:https://seer.ufrgs.br/dar/article/view/89766/53381

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