Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)

Abstract Background The pharmaceutical industry and the National Regulatory Authorities are now focusing on the quantification of multi-component drugs for quality control testing. Main body Recently, the utilization of the ultraviolet spectrophotometric methods has become vital for the analytical s...

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Main Authors:	Reem H. Obaydo, Duaa J. Al Zakri, Amir Alhaj Sakur, Hayam M. Lotfy
Format:	Article
Language:	English
Published:	SpringerOpen 2021-02-01
Series:	Future Journal of Pharmaceutical Sciences
Subjects:	Fixed-dose combinations drug Minor component Ultraviolet spectrophotometric methods
Online Access:	https://doi.org/10.1186/s43094-021-00192-9

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spelling	doaj-ccac0979dcdc4b5c9fc2b8921c34c8da2021-02-14T12:44:54ZengSpringerOpenFuture Journal of Pharmaceutical Sciences2314-72532021-02-01711910.1186/s43094-021-00192-9Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)Reem H. Obaydo0Duaa J. Al Zakri1Amir Alhaj Sakur2Hayam M. Lotfy3Department of Analytical and Food Chemistry, Faculty of Pharmacy, University of AleppoDepartment of Analytical and Food Chemistry, Faculty of Pharmacy, University of AleppoDepartment of Analytical and Food Chemistry, Faculty of Pharmacy, University of AleppoPharmaceutical Chemistry Department, Faculty of Pharmaceutical Science and Pharmaceutical Industries, Future University in EgyptAbstract Background The pharmaceutical industry and the National Regulatory Authorities are now focusing on the quantification of multi-component drugs for quality control testing. Main body Recently, the utilization of the ultraviolet spectrophotometric methods has become vital for the analytical studies for the routine analysis of different fixed-dose combination products either in the presence of a minor component in their combination or not. This article reviewed several published methods to those that have been applied to quantify some pharmaceutical combinations containing minor components through the last two decades. Conclusion The applied spectrophotometric methods are labor, time-saving, and also considered a cheap substitute for the overpriced high-performance liquid chromatographic technique.https://doi.org/10.1186/s43094-021-00192-9Fixed-dose combinations drugMinor componentUltraviolet spectrophotometric methods
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Reem H. Obaydo Duaa J. Al Zakri Amir Alhaj Sakur Hayam M. Lotfy
spellingShingle	Reem H. Obaydo Duaa J. Al Zakri Amir Alhaj Sakur Hayam M. Lotfy Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020) Future Journal of Pharmaceutical Sciences Fixed-dose combinations drug Minor component Ultraviolet spectrophotometric methods
author_facet	Reem H. Obaydo Duaa J. Al Zakri Amir Alhaj Sakur Hayam M. Lotfy
author_sort	Reem H. Obaydo
title	Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
title_short	Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
title_full	Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
title_fullStr	Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
title_full_unstemmed	Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
title_sort	ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)
publisher	SpringerOpen
series	Future Journal of Pharmaceutical Sciences
issn	2314-7253
publishDate	2021-02-01
description	Abstract Background The pharmaceutical industry and the National Regulatory Authorities are now focusing on the quantification of multi-component drugs for quality control testing. Main body Recently, the utilization of the ultraviolet spectrophotometric methods has become vital for the analytical studies for the routine analysis of different fixed-dose combination products either in the presence of a minor component in their combination or not. This article reviewed several published methods to those that have been applied to quantify some pharmaceutical combinations containing minor components through the last two decades. Conclusion The applied spectrophotometric methods are labor, time-saving, and also considered a cheap substitute for the overpriced high-performance liquid chromatographic technique.
topic	Fixed-dose combinations drug Minor component Ultraviolet spectrophotometric methods
url	https://doi.org/10.1186/s43094-021-00192-9
work_keys_str_mv	AT reemhobaydo ultravioletspectrophotometricmethodsforthedeterminationoftheminorcomponentpresentedinfixeddosepharmaceuticalcombinationsthroughthelasttwodecades20002020 AT duaajalzakri ultravioletspectrophotometricmethodsforthedeterminationoftheminorcomponentpresentedinfixeddosepharmaceuticalcombinationsthroughthelasttwodecades20002020 AT amiralhajsakur ultravioletspectrophotometricmethodsforthedeterminationoftheminorcomponentpresentedinfixeddosepharmaceuticalcombinationsthroughthelasttwodecades20002020 AT hayammlotfy ultravioletspectrophotometricmethodsforthedeterminationoftheminorcomponentpresentedinfixeddosepharmaceuticalcombinationsthroughthelasttwodecades20002020
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Ultraviolet spectrophotometric methods for the determination of the minor component presented in fixed-dose pharmaceutical combinations through the last two decades (2000–2020)

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