Measurement of neutralizing serum antibodies of patients vaccinated with human papillomavirus L1 or L2-based immunogens using furin-cleaved HPV Pseudovirions.

Antibodies specific for neutralizing epitopes in either Human papillomavirus (HPV) capsid protein L1 or L2 can mediate protection from viral challenge and thus their accurate and sensitive measurement at high throughput is likely informative for monitoring response to prophylactic vaccination. Here...

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Bibliographic Details
Main Authors: Joshua W Wang, Subhashini Jagu, Chenguang Wang, Henry C Kitchener, Sai Daayana, Peter L Stern, Susana Pang, Patricia M Day, Warner K Huh, Richard B S Roden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084990?pdf=render