Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats

The anti-obesity, appetite suppressant, diuretic and hipolipidemic effect of dried powdered leaves of Cordia salicifolia Cham (CS) were investigated. CS (20 mg.kg-1.day-1) dissolved in water was daily administered by gavage during 13 days. In contrast with the popular use as anti-obesity, appetite s...

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Main Authors: Vera Lúcia Dias Siqueira, Diógenes Aparicio Garcia Cortez, Carlos Eduardo de Oliveira, Celso Vataru Nakamura, Roberto Barbosa Bazotte
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2006-03-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000300005
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spelling doaj-cc9774115ed24a9ea55deb9ab023cee22020-11-24T21:26:31ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43242006-03-0149221521810.1590/S1516-89132006000300005Pharmacological studies of Cordia salicifolia Cham in normal and diabetic ratsVera Lúcia Dias SiqueiraDiógenes Aparicio Garcia CortezCarlos Eduardo de OliveiraCelso Vataru NakamuraRoberto Barbosa BazotteThe anti-obesity, appetite suppressant, diuretic and hipolipidemic effect of dried powdered leaves of Cordia salicifolia Cham (CS) were investigated. CS (20 mg.kg-1.day-1) dissolved in water was daily administered by gavage during 13 days. In contrast with the popular use as anti-obesity, appetite suppressant and diuretic, no effect were detected. However, hipolipidemic effect was observed in normal and alloxan-diabetic rats.<br>O efeito anti-obesidade, anorexigeno, diurético e anti-hiperlipêmico de folhas secas pulverizadas de Cordia salicifolia Cham (CS) foi investigado. CS foi dissolvida em água e administrada (20 mg.Kg-1.dia-1) por gavagem durante 13 dias. A dose utilizada correspondente à empregada no Brasil. Contrariamente ao uso popular, o efeito anti-obesidade, anorexigeno e diurético não foi observado. Porém, observamos efeito hipolipidêmico em ratos normais e portadores de diabetes induzidos por aloxana.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000300005Herbal therapieshipolipidemic activityporangabaCordia salicifolia
collection DOAJ
language English
format Article
sources DOAJ
author Vera Lúcia Dias Siqueira
Diógenes Aparicio Garcia Cortez
Carlos Eduardo de Oliveira
Celso Vataru Nakamura
Roberto Barbosa Bazotte
spellingShingle Vera Lúcia Dias Siqueira
Diógenes Aparicio Garcia Cortez
Carlos Eduardo de Oliveira
Celso Vataru Nakamura
Roberto Barbosa Bazotte
Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
Brazilian Archives of Biology and Technology
Herbal therapies
hipolipidemic activity
porangaba
Cordia salicifolia
author_facet Vera Lúcia Dias Siqueira
Diógenes Aparicio Garcia Cortez
Carlos Eduardo de Oliveira
Celso Vataru Nakamura
Roberto Barbosa Bazotte
author_sort Vera Lúcia Dias Siqueira
title Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
title_short Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
title_full Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
title_fullStr Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
title_full_unstemmed Pharmacological studies of Cordia salicifolia Cham in normal and diabetic rats
title_sort pharmacological studies of cordia salicifolia cham in normal and diabetic rats
publisher Instituto de Tecnologia do Paraná (Tecpar)
series Brazilian Archives of Biology and Technology
issn 1516-8913
1678-4324
publishDate 2006-03-01
description The anti-obesity, appetite suppressant, diuretic and hipolipidemic effect of dried powdered leaves of Cordia salicifolia Cham (CS) were investigated. CS (20 mg.kg-1.day-1) dissolved in water was daily administered by gavage during 13 days. In contrast with the popular use as anti-obesity, appetite suppressant and diuretic, no effect were detected. However, hipolipidemic effect was observed in normal and alloxan-diabetic rats.<br>O efeito anti-obesidade, anorexigeno, diurético e anti-hiperlipêmico de folhas secas pulverizadas de Cordia salicifolia Cham (CS) foi investigado. CS foi dissolvida em água e administrada (20 mg.Kg-1.dia-1) por gavagem durante 13 dias. A dose utilizada correspondente à empregada no Brasil. Contrariamente ao uso popular, o efeito anti-obesidade, anorexigeno e diurético não foi observado. Porém, observamos efeito hipolipidêmico em ratos normais e portadores de diabetes induzidos por aloxana.
topic Herbal therapies
hipolipidemic activity
porangaba
Cordia salicifolia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000300005
work_keys_str_mv AT veraluciadiassiqueira pharmacologicalstudiesofcordiasalicifoliachaminnormalanddiabeticrats
AT diogenesapariciogarciacortez pharmacologicalstudiesofcordiasalicifoliachaminnormalanddiabeticrats
AT carloseduardodeoliveira pharmacologicalstudiesofcordiasalicifoliachaminnormalanddiabeticrats
AT celsovatarunakamura pharmacologicalstudiesofcordiasalicifoliachaminnormalanddiabeticrats
AT robertobarbosabazotte pharmacologicalstudiesofcordiasalicifoliachaminnormalanddiabeticrats
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