Fever-range hyperthermia promotes cGAS-STING pathway and synergizes DMXAA-induced antiviral immunity

Fever-range hyperthermia promotes cGAS-STING pathway and synergizes DMXAA-induced antiviral immunity

Background: Fever-range hyperthermia or fever-range temperature (hereafter FRT) improves survival and shortens disease duration in microbial infections. However, the mechanisms of these beneficial effects still remain elusive. We hypothesized that FRT might enhance cell responsiveness to infections...

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Bibliographic Details
Main Authors: Inam Ullah Khan, Gabriel Brooks, Nina Ni Guo, Junsong Chen, Fang Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:International Journal of Hyperthermia
Subjects:
fever-range hyperthermia
dxmaa
antiviral immunity
ifn-β
cgas-sting
Online Access:http://dx.doi.org/10.1080/02656736.2020.1868582

Internet

http://dx.doi.org/10.1080/02656736.2020.1868582

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