Osteoimmuno-Oncology: Therapeutic Opportunities for Targeting Immune Cells in Bone Metastasis

Osteoimmuno-Oncology: Therapeutic Opportunities for Targeting Immune Cells in Bone Metastasis

Immunotherapies provide a potential treatment option for currently incurable bone metastases. Bone marrow is an important secondary lymphoid organ with a unique immune contexture. Even at non-disease state immune cells and bone cells interact with each other, bone cells supporting the development of...

Full description

Bibliographic Details
Main Authors:	Tiina E. Kähkönen, Jussi M. Halleen, Jenni Bernoulli
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Cells
Subjects:	osteoimmuno-oncology immuno-oncology osteoimmunology immunotherapy bone metastasis
Online Access:	https://www.mdpi.com/2073-4409/10/6/1529

Similar Items

Immunotherapies and Metastatic Cancers: Understanding Utility and Predictivity of Human Immune Cell Engrafted Mice in Preclinical Drug Development
by: Tiina E. Kähkönen, et al.
Published: (2020-06-01)

Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology
by: Maria J. Barrero
Published: (2020-09-01)

Alternative metrics for assessing clinical benefit with immunotherapy in oncology
by: E. Chan, et al.
Published: (2019-10-01)

Future prospects for breast cancer immunotherapy
by: V. F. Semiglazov, et al.
Published: (2018-11-01)

A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity
by: Nadine Nelson, et al.
Published: (2019-08-01)

The Immunotherapy Landscape in Adrenocortical Cancer
by: Guillaume J. Pegna, et al.
Published: (2021-05-01)

Further Advances in Cancer Immunotherapy: Going Beyond Checkpoint Blockade
by: Robert W. Wilkinson, et al.
Published: (2018-06-01)

Thromboembolic Events Related to Treatment with Checkpoint Inhibitors: Report of Two Cases
by: Jessica Tsukamoto, et al.
Published: (2018-10-01)

Immuno-oncology: are TAM receptors in glioblastoma friends or foes?
by: Yunxiang Zhou, et al.
Published: (2021-01-01)

The promise of Immuno-oncology: implications for defining the value of cancer treatment
by: Howard L. Kaufman, et al.
Published: (2019-05-01)

TCMIO: A Comprehensive Database of Traditional Chinese Medicine on Immuno-Oncology
by: Zhihong Liu, et al.
Published: (2020-04-01)

The changing face of clinical trials in the personalized medicine and immuno-oncology era: report from the international congress on clinical trials in Oncology & Hemato-Oncology (ICTO 2017)
by: Talia Golan, et al.
Published: (2017-12-01)

Monocytes and cancer: promising role as a diagnostic marker and application in therapy
by: M. R. Patysheva, et al.
Published: (2019-05-01)

Combination of Immunotherapy and Radiotherapy for Recurrent Malignant Gliomas: Results From a Prospective Study
by: Haihui Jiang, et al.
Published: (2021-05-01)

Accelerating patient access to oncology medicines with multiple indications in Europe
by: R. Lawlor, et al.
Published: (2021-01-01)

The New Immuno-Oncology-Based Therapies and Their Perspectives in Hepatocellular Carcinoma
by: Philippe Merle
Published: (2021-01-01)

Lights and Shadows in Immuno-Oncology Drug Development
by: Milana Bergamino Sirvén, et al.
Published: (2021-02-01)

Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer
by: Yuanyuan Shen, et al.
Published: (2020-02-01)

Bone Metabolism and Osteoporosis in Oncological Practice
by: Yu.V. Dumanskyi, et al.
Published: (2015-08-01)

Novel Immuno-oncology Therapy: Current Status of Clinical Research and Prospect of Application
by: Shijia ZHANG, et al.
Published: (2017-09-01)

Treatment of Primary and Metastatic Multifocal Mucosal Melanoma of the Oral Cavity with Imatinib
by: Teresa Deinlein, et al.
Published: (2017-06-01)

Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations
by: Madyson Colton, et al.
Published: (2020-11-01)

Gut microbiome and CAR-T therapy
by: Muhammad Bilal Abid, et al.
Published: (2019-11-01)

Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration
by: Mark N. Stein, et al.
Published: (2019-05-01)

Port-site metastases: Considerations for laparoscopic oncologic surgeries
by: LIU Quanda
Published: (2013-03-01)

Models and Mechanisms of Prostate Cancer Bone Metastasis
by: Simmons, Jessica Kelly
Published: (2014)

Lights and Shadows on Managing Immune Checkpoint Inhibitors in Oncology during the COVID-19 Era
by: Chiara Burgaletto, et al.
Published: (2021-04-01)

MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer types
by: Szu-Yuan Wu, et al.
Published: (2021-01-01)

Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology
by: Kirill Peskov, et al.
Published: (2019-04-01)

Innovative Options for Bone Metastasis Treatment: An Extensive Analysis on Biomaterials-Based Strategies for Orthopedic Surgeons
by: Ania Naila Guerrieri, et al.
Published: (2020-10-01)

Cancer DNA vaccines: current preclinical and clinical developments and future perspectives
by: Alessandra Lopes, et al.
Published: (2019-04-01)

Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy
by: Robainas M, et al.
Published: (2017-03-01)

NHS-IL12, a Tumor-Targeting Immunocytokine
by: Greiner JW, et al.
Published: (2021-05-01)

mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?
by: Azzurra Irelli, et al.
Published: (2019-11-01)

Bringing the Next Generation of Immuno-Oncology Biomarkers to the Clinic
by: Alessandra Cesano, et al.
Published: (2018-02-01)

Modeling the economic outcomes of immuno-oncology drugs: alternative model frameworks to capture clinical outcomes
by: Gibson EJ, et al.
Published: (2018-03-01)

Applying Precision Medicine and Immunotherapy Advances from Oncology to Host-Directed Therapies for Infectious Diseases
by: Robert N. Mahon, et al.
Published: (2017-06-01)

Leveraging NKG2D Ligands in Immuno-Oncology
by: Mercedes Beatriz Fuertes, et al.
Published: (2021-07-01)

Radiotherapy–Immunotherapy Combination: How Will We Bridge the Gap Between Pre-Clinical Promise and Effective Clinical Delivery?
by: Erminia Romano, et al.
Published: (2021-01-01)

The Microbiome and Its Implications in Cancer Immunotherapy
by: Hani Choudhry
Published: (2021-01-01)

Cannot write session to /tmp/vufind_sessions/sess_i9j1575ctnsflbunuafpltpuh1