Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration

Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration

Abstract Background Exosomes are extracellular vesicles that mediate cellular communication in health and diseases. Neutrophils could be polarized to a pro-tumor phenotype by tumor. The function of tumor-derived exosomes in neutrophil regulation remains unclear. Methods We investigated the effects o...

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Bibliographic Details
Main Authors: Xu Zhang, Hui Shi, Xiao Yuan, Pengcheng Jiang, Hui Qian, Wenrong Xu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Molecular Cancer
Subjects:
Exosome
Neutrophil
Gastric cancer
Pro-tumor
Activation
Autophagy
Online Access:http://link.springer.com/article/10.1186/s12943-018-0898-6

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