Combined In Vitro Studies and in Silico Target Fishing for the Evaluation of the Biological Activities of <i>Diphylleia cymosa</i> and <i>Podophyllum hexandrum</i>

Combined In Vitro Studies and in Silico Target Fishing for the Evaluation of the Biological Activities of <i>Diphylleia cymosa</i> and <i>Podophyllum hexandrum</i>

This paper reports the in silico prediction of biological activities of lignans from <i>Diphylleia cymosa</i> and <i>Podophyllum hexandrum</i> combined with an in vitro bioassays. The extracts from the leaves, roots and rhizomes of both species were evaluated for their antiba...

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Bibliographic Details
Main Authors: Marina Pereira Rocha, Priscilla Rodrigues Valadares Campana, Denise de Oliveira Scoaris, Vera Lucia de Almeida, Julio Cesar Dias Lopes, Julian Mark Hugh Shaw, Claudia Gontijo Silva
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
lignans
in silico studies
podophyllotoxin
antibacterial activity
acetylcholinesterase inhibitors
antioxidant activity
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/23/12/3303

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