SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer.

SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer.

Sporadic colorectal cancer (CRC) is a common malignancy and also one of the main causes of cancer deaths worldwide. Aberrant expression of the transcription factor SOX2 has recently been observed in several cancer types, but its role in CRC has not been fully elucidated. Here we studied the expressi...

Full description

Bibliographic Details
Main Authors: Ida V Lundberg, Anna Löfgren Burström, Sofia Edin, Vincy Eklöf, Åke Öberg, Roger Stenling, Richard Palmqvist, Maria L Wikberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4092103?pdf=render

Similar Items

Similar Items