Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems

Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems

A major hurdle for in vitro culturing of primary endothelial cells (ECs) is that they readily dedifferentiate, hampering their use for therapeutic applications. Human embryonic stem cells (hESCs) may provide an unlimited cell source; however, most current protocols deriving endothelial progenitor ce...

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Bibliographic Details
Main Authors: Mien T.X. Nguyen, Elena Okina, Xiaoran Chai, Kok Hian Tan, Outi Hovatta, Sujoy Ghosh, Karl Tryggvason
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301849

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