A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes

A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes

Abstract Background Efficient high-throughput drug screening assays are necessary to enable the discovery of new anti-mycobacterial drugs. The purpose of our work was to develop and validate an assay based on live-cell imaging which can monitor the growth of two distinct phenotypes of Mycobacterium...

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Bibliographic Details
Main Authors:	Sadaf Kalsum, Blanka Andersson, Jyotirmoy Das, Thomas Schön, Maria Lerm
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Series:	BMC Microbiology
Subjects:	Cording Planktonic Mycobacterium tuberculosis Whole-cell screening Automated live-cell imaging
Online Access:	https://doi.org/10.1186/s12866-021-02212-3

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