Different Vancomycin Immunoassays Contribute to the Variability in Vancomycin Trough Measurements in Neonates
Substantial interassay variability (up to 20%) has been described for vancomycin immunoassays in adults, but the impact of neonatal matrix is difficult to quantify because of blood volume constraints in neonates. However, we provide circumstantial evidence for a similar extent of variability. Using...
Main Authors: | Janko Samardzic, Anne Smits, Isabel Spriet, Ivan Soldatovic, Andrew Atkinson, Milica Bajcetic, John N. Van Den Anker, Karel Allegaert |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2016/1974972 |
Similar Items
-
Amikacin or Vancomycin Exposure Alters the Postnatal Serum Creatinine Dynamics in Extreme Low Birth Weight Neonates
by: Tamara van Donge, et al.
Published: (2021-01-01) -
Clinical pharmacokinetics of vancomycin in the neonate: a review
by: Gian Maria Pacifici, et al.
Published: (2012-07-01) -
Vancomycin trough level and loading dose
by: Tuon FF, et al.
Published: (2018-11-01) -
Prospective validation of neonatal vancomycin dosing regimens is urgently needed
by: Anaïs Vandendriessche, MD, et al.
Published: (2014-12-01) -
Validation of a immunoassay for the determination of vancomycin in cerebospinal fluid.
by: Lucrecia Marks, et al.
Published: (2019-06-01)