Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44<sup>high</sup>/cd24<sup>low </sup>population which is invasive and resistant to anoikis

Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44<sup>high</sup>/cd24<sup>low </sup>population which is invasive and resistant to anoikis

<p>Abstract</p> <p>Background</p> <p>The Wnt family of secreted proteins is implicated in the regulation of cell fate during development, as well as in cell proliferation, morphology, and migration. Aberrant activation of the Wnt/β-catenin signaling pathway leads to the...

Full description

Bibliographic Details
Main Authors: Hugh Jeremy M, Troester Melissa A, Gauger Kelly J, Schneider Sallie
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/9/1/11

Similar Items

Similar Items