Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44<sup>high</sup>/cd24<sup>low </sup>population which is invasive and resistant to anoikis
<p>Abstract</p> <p>Background</p> <p>The Wnt family of secreted proteins is implicated in the regulation of cell fate during development, as well as in cell proliferation, morphology, and migration. Aberrant activation of the Wnt/β-catenin signaling pathway leads to the...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-05-01
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| Series: | Cancer Cell International |
| Online Access: | http://www.cancerci.com/content/9/1/11 |