Assessment of intratumoral heterogeneity with mutations and gene expression profiles.

Assessment of intratumoral heterogeneity with mutations and gene expression profiles.

Intratumoral heterogeneity (ITH) refers to the presence of distinct tumor cell populations. It provides vital information for the clinical prognosis, drug responsiveness, and personalized treatment of cancer patients. As genomic ITH in various cancers affects the expression patterns of genes, the ex...

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Bibliographic Details
Main Authors:	Ji-Yong Sung, Hyun-Tae Shin, Kyung-Ah Sohn, Soo-Yong Shin, Woong-Yang Park, Je-Gun Joung
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0219682

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