TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone.

TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone.

Somatosensory information from the periphery is routed to the spinal cord through centrally-projecting sensory axons that cross into the central nervous system (CNS) via the dorsal root entry zone (DREZ). The glial cells that ensheath these axons ensure rapid propagation of this information. Despite...

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Bibliographic Details
Main Authors: Cody J Smith, Michael A Wheeler, Lindsay Marjoram, Michel Bagnat, Christopher D Deppmann, Sarah Kucenas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5397050?pdf=render

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