TAZ Mediates Lysophosphatidic Acid-Induced Migration and Proliferation of Epithelial Ovarian Cancer Cells

TAZ Mediates Lysophosphatidic Acid-Induced Migration and Proliferation of Epithelial Ovarian Cancer Cells

Background: Transcriptional co-activator with PDZ-binding motif (TAZ), a downstream effector of the Hippo pathway, has been reported to regulate organ size, tissue homeostasis, and tumorigenesis by acting as a transcriptional co-activator. Lysophosphatidic acid (LPA) is a bioactive lipid implicated...

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Bibliographic Details
Main Authors: Geun Ok Jeong, Sang Hun Shin, Eun Jin Seo, Yang Woo Kwon, Soon Chul Heo, Ki-Hyung Kim, Man-Soo Yoon, Dong-Soo Suh, Jae Ho Kim
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Lysophosphatidic acid
TAZ
Ovarian cancer
Migration
Proliferation
Online Access:http://www.karger.com/Article/FullText/354434

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