IgM promotes the clearance of small particles and apoptotic microparticles by macrophages.

Antibodies are often involved in enhancing particle clearance by macrophages. Although the mechanisms of antibody-dependent phagocytosis have been studied for IgG in greater detail, very little is known about IgM-mediated clearance. It has been generally considered that IgM does not support phagocyt...

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Bibliographic Details
Main Authors: Michael L Litvack, Martin Post, Nades Palaniyar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063157?pdf=render