IgM promotes the clearance of small particles and apoptotic microparticles by macrophages.
Antibodies are often involved in enhancing particle clearance by macrophages. Although the mechanisms of antibody-dependent phagocytosis have been studied for IgG in greater detail, very little is known about IgM-mediated clearance. It has been generally considered that IgM does not support phagocyt...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3063157?pdf=render |