Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures

<p>Abstract</p> <p>Background</p> <p>Cytokine-induced killer (CIK) cells are typically differentiated <it>in vitro </it>with interferon (IFN)-γ and αCD3 monoclonal antibodies (mAb), followed by the repeated provision of interleukin (IL)-2. It is presently un...

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Bibliographic Details
Main Authors: Corallo Maria, Fioravanti Daniela, Pandolfi Annino, Procoli Annabella, Mariotti Andrea, Iudicone Paola, Bonanno Giuseppina, Perillo Alessandro, Scambia Giovanni, Pierelli Luca, Rutella Sergio
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/129