Metabolism of cholesteryl palmitate by rat brain in vitro; formation of cholesterol epoxides and cholestane-3β,5α,6β-triol
Incubation of [4-14C] cholesteryl palmitate with the 12,000 g supernatant fraction of adult rat brain fortified with an NADPH-generating system and β-mercaptoethylamine resulted in formation (2–5%) of more polar metabolites characterized as a mixture of cholesterol-5,6-epoxides. Under extended incub...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1973-11-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520368425 |