Mild and efficient cyanuric chloride catalyzed Pictet–Spengler reaction

Mild and efficient cyanuric chloride catalyzed Pictet–Spengler reaction

A practical, mild and efficient protocol for the Pictet–Spengler reaction catalyzed by cyanuric chloride (trichloro-1,3,5-triazine, TCT) is described. The 6-endo cyclization of tryptophan/tryptamine and modified Pictet–Spengler substrates with both electron-withdrawing and electron-donating aldehyde...

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Bibliographic Details
Main Authors: Ashish Sharma, Mrityunjay Singh, Nitya Nand Rai, Devesh Sawant
Format: Article
Language:English
Published: Beilstein-Institut 2013-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
β-carboline
cyanuric chloride
6-endo cyclization
Pictet–Spengler
TCT
Online Access:https://doi.org/10.3762/bjoc.9.140

Internet

https://doi.org/10.3762/bjoc.9.140

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