Preferential colonization of metastases by oncolytic vaccinia virus strain GLV-1h68 in a human PC-3 prostate cancer model in nude mice.

Preferential colonization of metastases by oncolytic vaccinia virus strain GLV-1h68 in a human PC-3 prostate cancer model in nude mice.

Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a significant therapeutic potential in treating lymph node metastases of human PC-3 prostate carcinoma in tumor xenografts. In this study, underlying mechanisms of the virus-mediated metastases reduction were analyzed. Immunohistoche...

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Bibliographic Details
Main Authors: Ulrike Donat, Stephanie Weibel, Michael Hess, Jochen Stritzker, Barbara Härtl, Julia B Sturm, Nanhai G Chen, Ivaylo Gentschev, Aladar A Szalay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457966?pdf=render

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http://europepmc.org/articles/PMC3457966?pdf=render

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