Tryptophan and Kynurenic Acid May Produce an Amplified Effect in Central Fatigue Induced by Chronic Sleep Disorder

Tryptophan (TRP) and its neuroactive metabolite, kynurenic acid (KYNA), are thought to play key roles in central fatigue, but the specifics are still unknown. To clarify their roles in the brain, we developed a rat model of central fatigue induced by chronic sleep disorder (CFSD) by disturbing the s...

Full description

Bibliographic Details
Main Authors: Masatoshi Yamashita, Takanobu Yamamoto
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:International Journal of Tryptophan Research
Online Access:https://doi.org/10.4137/IJTR.S14084

Similar Items