Cold atmospheric plasma and silymarin nanoemulsion synergistically inhibits human melanoma tumorigenesis via targeting HGF/c-MET downstream pathway

Cold atmospheric plasma and silymarin nanoemulsion synergistically inhibits human melanoma tumorigenesis via targeting HGF/c-MET downstream pathway

Abstract Background Recent studies claimed the important role of cold atmospheric plasma (CAP) with nanotechnology in cancer treatments. In this study, silymarin nanoemulsion (SN) was used along with air CAP as therapeutic agent to counter human melanoma. Methods In this study, we examined the combi...

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Bibliographic Details
Main Authors: Manish Adhikari, Neha Kaushik, Bhagirath Ghimire, Bhawana Adhikari, Sanjula Baboota, Abdulaziz A. Al-Khedhairy, Rizwan Wahab, Su-Jae Lee, Nagendra Kumar Kaushik, Eun Ha Choi
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cell Communication and Signaling
Subjects:
Non thermal plasma
Silymarin nanoemulsion
Melanoma
HGF/c-MET
Cancer Stemness
Epithelial-mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s12964-019-0360-4

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