Berberine alters gut microbial function through modulation of bile acids

Berberine alters gut microbial function through modulation of bile acids

Abstract Background Berberine (BBR) is a plant-based nutraceutical that has been used for millennia to treat diarrheal infections and in contemporary medicine to improve patient lipid profiles. Reduction in lipids, particularly cholesterol, is achieved partly through up-regulation of bile acid synth...

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Bibliographic Details
Main Authors: Patricia G. Wolf, Saravanan Devendran, Heidi L. Doden, Lindsey K. Ly, Tyler Moore, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, George E. Chlipala, Stefan J. Green, Genta Kakiyama, Purna Kashyap, Vance J. McCracken, H. Rex Gaskins, Patrick M. Gillevet, Jason M. Ridlon
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Microbiology
Subjects:
Berberine
Bile acids
Gnotobiotic mice
Gut bacteria
Network analysis
Nutraceutical
Online Access:https://doi.org/10.1186/s12866-020-02020-1

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