The impact of septic stimuli on the systemic inflammatory response and physiologic insult in a preclinical non-human primate model of polytraumatic injury

The impact of septic stimuli on the systemic inflammatory response and physiologic insult in a preclinical non-human primate model of polytraumatic injury

Abstract Background Established animal trauma models are limited in recapitulating the pathophysiology of human traumatic injury. Herein, we characterize the physiologic insult and inflammatory response in two clinically relevant non-human primate (NHP) trauma models. Methods Mauritian Cynomolgus Ma...

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Bibliographic Details
Main Authors: Diego A. Vicente, Matthew J. Bradley, Benjamin Bograd, Crystal Leonhardt, Eric A. Elster, Thomas A. Davis
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Inflammation
Subjects:
Inflammation
Trauma
Sepsis
Hemorrhage
Animal model
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12950-018-0187-6

Internet

http://link.springer.com/article/10.1186/s12950-018-0187-6

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