Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

The bone marrow (BM) microenvironment plays a crucial role in the maintenance and regeneration of hematopoietic stem (HSC) and progenitor cells (HSPC). In particular, the vascular niche is responsible for regulating HSC maintenance, differentiation, and migration of cells in and out of the BM. Damag...

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Bibliographic Details
Main Authors: Lynnette Cary, Daniel Noutai, Rudolph Salber, Opeyemi Fadiyimu, Arthur Gross, Graca Almeida-Porada, Yared Kidane, Mark Whitnall
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
n/a
Online Access:https://www.mdpi.com/1422-0067/20/7/1795

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