The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Overexpression of the RON receptor tyrosine kinase contributes to epithelial cell transformation, malignant progression, and acquired drug resistance. RON also has been considered as a potential target for therapeutic intervention. T...

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Bibliographic Details
Main Authors: Zhang Rui-Wen, Padhye Snehal S, Guin Sunny, Ma Qi, Zhou Yong-Qing, Yao Hang-Ping, Wang Ming-Hai
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/82