Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of chagas disease

Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical course, ranging from symptomless infection to severe chronic disease with cardiovascular or gastrointestinal involvement or, occasionally, overwhelming acute episodes. The factors influencing this clinical variability...

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Bibliographic Details
Main Authors: Andréa M Macedo, Carlos R Machado, Riva P Oliveira, Sérgio DJ Pena
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000100001