D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients

The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism...

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Main Authors: Yael Becher, Leonid Goldman, Nadav Schacham, Irina Gringauz, Dan Justo
Format: Article
Language:English
Published: SMC MEDIA SRL 2020-05-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/1725
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spelling doaj-cbf1a183213348bface7b0975296389b2020-11-25T03:17:38ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942020-05-0110.12890/2020_0017251359D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 PatientsYael Becher0Leonid Goldman1Nadav Schacham2Irina Gringauz3Dan Justo4Geriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, IsraelGeriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, IsraelGeriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, IsraelGeriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, IsraelGeriatrics and Internal Medicine B Department, Sheba Medical Center, Ramat-Gan, Israel; Aff. to Sackler School of Medicine, Tel-Aviv University, IsraelThe diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.https://www.ejcrim.com/index.php/EJCRIM/article/view/1725covid-19c-reactive proteind-dimerpulmonary embolism
collection DOAJ
language English
format Article
sources DOAJ
author Yael Becher
Leonid Goldman
Nadav Schacham
Irina Gringauz
Dan Justo
spellingShingle Yael Becher
Leonid Goldman
Nadav Schacham
Irina Gringauz
Dan Justo
D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
European Journal of Case Reports in Internal Medicine
covid-19
c-reactive protein
d-dimer
pulmonary embolism
author_facet Yael Becher
Leonid Goldman
Nadav Schacham
Irina Gringauz
Dan Justo
author_sort Yael Becher
title D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_short D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_full D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_fullStr D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_full_unstemmed D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_sort d-dimer and c-reactive protein blood levels over time used to predict pulmonary embolism in two covid-19 patients
publisher SMC MEDIA SRL
series European Journal of Case Reports in Internal Medicine
issn 2284-2594
publishDate 2020-05-01
description The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.
topic covid-19
c-reactive protein
d-dimer
pulmonary embolism
url https://www.ejcrim.com/index.php/EJCRIM/article/view/1725
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