Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells

Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells

<p>Abstract</p> <p>Background</p> <p>Asthma causes significant morbidity worldwide in adults and children alike, and incurs large healthcare costs. The statin drugs, which treat hyperlipidemia and cardiovascular diseases, have pleiotropic effects beyond lowering cholest...

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Bibliographic Details
Main Authors: Zeki Amir A, Thai Phil, Kenyon Nicholas J, Wu Reen
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Respiratory Research
Subjects:
Statin
Asthma
Mevalonate pathway
Airway epithelium
HMG-CoA reductase
Cytokines
Chemokines
Gene expression
Mouse tracheal epithelium
Online Access:http://respiratory-research.com/content/13/1/38

Internet

http://respiratory-research.com/content/13/1/38

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