HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy

HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy

The majority of new HIV-1 infections occur in young adults, with adolescent women being 3 times more likely to acquire HIV than young men. Implementation of HIV prevention strategies has been less successful in this age group; thus, a vaccine given prior to adolescence remains a high priority. We pr...

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Bibliographic Details
Main Authors: Alan D. Curtis, Maria Dennis, Joshua Eudailey, Korey L. Walter, Kenneth Cronin, S. Munir Alam, Neelima Choudhary, Ryan H. Tuck, Michael Hudgens, Pamela A. Kozlowski, Justin Pollara, Guido Ferrari, Koen K. A. Van Rompay, Sallie Permar, Kristina De Paris
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mSphere
Subjects:
hiv
pediatric vaccination
memory antibody responses
adjuvant
Online Access:https://doi.org/10.1128/mSphere.00162-20

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