Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma

<p>Abstract</p> <p>Background</p> <p>Exposure to chlorine (Cl<sub>2</sub>) causes airway injury, characterized by oxidative damage, an influx of inflammatory cells and airway hyperresponsiveness. We hypothesized that Cl<sub>2</sub>-induced airway...

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Bibliographic Details
Main Authors: Lavoie Normand, Karmouty-Quintana Harry, Govindaraju Karuthapillai, White Carl W, Day Brian J, Powell William S, McGovern Toby K, Tan Ju Jing, Martin James G
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/138