Knockdown of PLC-gamma-2 and calmodulin 1 genes sensitizes human cervical adenocarcinoma cells to doxorubicin and paclitaxel

Knockdown of PLC-gamma-2 and calmodulin 1 genes sensitizes human cervical adenocarcinoma cells to doxorubicin and paclitaxel

<p>Abstract</p> <p>Background</p> <p>RNA interference (RNAi) is a powerful approach in functional genomics to selectively silence messenger mRNA (mRNA) expression and can be employed to rapidly develop potential novel drugs against a complex disease like cancer. However...

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Bibliographic Details
Main Authors: Stanislaus Anthony, Bakhtiar Athirah, Salleh Diyana, Tiash Snigdha, Fatemian Tahereh, Hossain Sharif, Akaike Toshihiro, Chowdhury Ezharul
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Cancer Cell International
Subjects:
Carbonate apatite
Nanoparticle
siRNA
PLC-gamma-2
Calmodulin 1
Cervical cancer
Cisplatin
Doxorubicin
Paclitaxel
Online Access:http://www.cancerci.com/content/12/1/30

Internet

http://www.cancerci.com/content/12/1/30

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