Heat Shock Proteins and Neurodegenerative Disorders

Heat Shock Proteins and Neurodegenerative Disorders

Heat shock proteins (HSPs) are evolutionarily conserved molecules and play important roles in fundamental cellular processes. They serve as molecular chaperones and hence provide a protective function in ensuring cell survival and repair of cellular damage after a stressful stimulus. This paper summ...

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Main Authors: Eliza Ting-Li Soo, Yee-Kong Ng, Boon-Huat Bay, George Wai-Cheong Yip
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2008.48
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spelling doaj-cbd3c863a83d44189d41b1332c8e49f52020-11-25T00:27:22ZengHindawi LimitedThe Scientific World Journal1537-744X2008-01-01827027410.1100/tsw.2008.48Heat Shock Proteins and Neurodegenerative DisordersEliza Ting-Li Soo0Yee-Kong Ng1Boon-Huat Bay2George Wai-Cheong Yip3Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, Singapore 117597, SingaporeDepartment of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, Singapore 117597, SingaporeDepartment of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, Singapore 117597, SingaporeDepartment of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 4 Medical Drive, Block MD10, Singapore 117597, SingaporeHeat shock proteins (HSPs) are evolutionarily conserved molecules and play important roles in fundamental cellular processes. They serve as molecular chaperones and hence provide a protective function in ensuring cell survival and repair of cellular damage after a stressful stimulus. This paper summarizes the current knowledge about the different roles of HSPs in aging and disease, focusing on the neurodegenerative disorders of Alzheimer's disease, Parkinson's disease, Huntington's disease, and prion disease.http://dx.doi.org/10.1100/tsw.2008.48
collection DOAJ
language English
format Article
sources DOAJ
author Eliza Ting-Li Soo
Yee-Kong Ng
Boon-Huat Bay
George Wai-Cheong Yip
spellingShingle Eliza Ting-Li Soo
Yee-Kong Ng
Boon-Huat Bay
George Wai-Cheong Yip
Heat Shock Proteins and Neurodegenerative Disorders
The Scientific World Journal
author_facet Eliza Ting-Li Soo
Yee-Kong Ng
Boon-Huat Bay
George Wai-Cheong Yip
author_sort Eliza Ting-Li Soo
title Heat Shock Proteins and Neurodegenerative Disorders
title_short Heat Shock Proteins and Neurodegenerative Disorders
title_full Heat Shock Proteins and Neurodegenerative Disorders
title_fullStr Heat Shock Proteins and Neurodegenerative Disorders
title_full_unstemmed Heat Shock Proteins and Neurodegenerative Disorders
title_sort heat shock proteins and neurodegenerative disorders
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2008-01-01
description Heat shock proteins (HSPs) are evolutionarily conserved molecules and play important roles in fundamental cellular processes. They serve as molecular chaperones and hence provide a protective function in ensuring cell survival and repair of cellular damage after a stressful stimulus. This paper summarizes the current knowledge about the different roles of HSPs in aging and disease, focusing on the neurodegenerative disorders of Alzheimer's disease, Parkinson's disease, Huntington's disease, and prion disease.
url http://dx.doi.org/10.1100/tsw.2008.48
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AT yeekongng heatshockproteinsandneurodegenerativedisorders
AT boonhuatbay heatshockproteinsandneurodegenerativedisorders
AT georgewaicheongyip heatshockproteinsandneurodegenerativedisorders
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