Genome-Scale Assessment of Age-Related DNA Methylation Changes in Mouse Spermatozoa.
DNA methylation plays important roles in the production and functioning of spermatozoa. Recent studies have suggested that DNA methylation patterns in spermatozoa can change with age, but the regions susceptible to age-related methylation changes remain to be fully elucidated. In this study, we cond...
Main Authors: | Norio Kobayashi, Hiroaki Okae, Hitoshi Hiura, Hatsune Chiba, Yoshiki Shirakata, Kenshiro Hara, Kentaro Tanemura, Takahiro Arima |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5120852?pdf=render |
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