Elafibranor Inhibits Chronic Kidney Disease Progression in NASH Mice

Identification of new pharmacological approaches to inhibit the excessive fat intake-induced steatohepatitis and chronic kidney disease (CKD) is important. High-fat diet (HFD)-induced steatohepatitis and CKD share common pathogenesis involving peroxisome proliferator-activated receptor (PPAR)-α and...

Full description

Bibliographic Details
Main Authors: Hung-Cheng Tsai, Fu-Pang Chang, Tzu-Hao Li, Chih-Wei Liu, Chia-Chang Huang, Shiang-Fen Huang, Ying-Ying Yang, Kuei-Chuan Lee, Yun-Cheng Hsieh, Ying-Wen Wang, Tzung-Yan Lee, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/6740616