A genome-wide association study of optic disc parameters.
The optic nerve head is involved in many ophthalmic disorders, including common diseases such as myopia and open-angle glaucoma. Two of the most important parameters are the size of the optic disc area and the vertical cup-disc ratio (VCDR). Both are highly heritable but genetically largely undeterm...
Main Authors: | Wishal D Ramdas, Leonieke M E van Koolwijk, M Kamran Ikram, Nomdo M Jansonius, Paulus T V M de Jong, Arthur A B Bergen, Aaron Isaacs, Najaf Amin, Yurii S Aulchenko, Roger C W Wolfs, Albert Hofman, Fernando Rivadeneira, Ben A Oostra, Andre G Uitterlinden, Pirro Hysi, Christopher J Hammond, Hans G Lemij, Johannes R Vingerling, Caroline C W Klaver, Cornelia M van Duijn |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2883590?pdf=render |
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