Infectivity and viability of dengue virus infected hepatocytes cocultured with peripheral blood mononuclear cells from a healthy subject

Infectivity and viability of dengue virus infected hepatocytes cocultured with peripheral blood mononuclear cells from a healthy subject

BACKGROUND Dengue virus (DENV) can infect and replicate in monocytes, resulting in antibody-dependent enhancement. The liver is the main target of DENV, and the infection mechanisms of DENV include direct cytopathic effects (CPEs) of the virus, mitochondrial dysfunction, and effect of cellular and...

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Bibliographic Details
Main Authors: Sekar Asri Tresnaningtyas, Fithriyah Sjatha, Beti Ernawati Dewi
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2020-10-01
Series:Medical Journal of Indonesia
Subjects:
dengue
hepatocytes
in vitro
liver
monocytes
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/3433

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