Development and validation of a reversed-phase HPLC method for analysis of tetrahydrozoline hydrochloride in eye drop formulations

A simple, precise, accurate, and stability-indicating method is developed and validated for analysis of tetrahydrozoline hydrochloride in eye drop formulations. Separation was achieved on a reversed-phase C8 column (125 mmÃ4.6 mm i.d., 5 μm) using a mobile phase consisting of acetonitrile/phosph...

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Bibliographic Details
Main Authors: Fuad Al-Rimawi, Wahbeh Zareer, Salah Rabie, Mazen Quod
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177911000414