Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy.

Genetic diversity of the KIR/HLA system and outcome of patients with metastatic colorectal cancer treated with chemotherapy.

To explore genes of the killer-cell immunoglobulin-like receptor (KIR) and of the HLA ligand and their relationship with the outcome of metastatic colorectal cancer (mCRC) patients treated with first-line 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI).A total of 224 mCRC patients were screened...

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Main Authors: Valli De Re, Laura Caggiari, Mariangela De Zorzi, Renato Talamini, Vito Racanelli, Mario D' Andrea, Angela Buonadonna, Vittorina Zagonel, Erika Cecchin, Federico Innocenti, Giuseppe Toffoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3908861?pdf=render

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