The contact activation system and vascular factors as alternative targets for Alzheimer's disease therapy

Abstract Alzheimer's disease (AD) is the most common neurodegenerative disease, affecting millions of people worldwide. Extracellular beta‐amyloid (Aβ) plaques and neurofibrillary tau tangles are classical hallmarks of AD pathology and thus are the prime targets for AD therapeutics. However, ap...

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Bibliographic Details
Main Authors: Pradeep K. Singh, Ana Badimon, Zu‐Lin Chen, Sidney Strickland, Erin H. Norris
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12504