Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients

Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients

Background: Somatic mutations in isocitrate dehydrogenase 1 (IDH1) gene occur frequently in primary brain tumors. Recently theses mutations were demonstrated in acute myeloid leukemia (AML). So far, assessment of these mutations relied on the DNA sequencing technique. Aim of the work: The aim of thi...

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Bibliographic Details
Main Authors: Ghada M. Elsayed, Hanan R. Nassar, Amr Zaher, Essam H. Elnoshokaty, Manar M. Moneer
Format: Article
Language:English
Published: SpringerOpen 2014-03-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
AML
IDH1 mutation
PCR-RFLP
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1110036213001106

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